Archive 1995–2023

Huntington's disease (HD) is a progressive neurodegenerative disease. Although the symptoms have been known for 150 years, there is still no effective treatment. Frequently, patients with HD experience co-occurring symptoms, such as mood swings, psychotic disturbances or aggression, thus many pharmacological interventions are undertaken with the aim of eliminating these
symptoms. This paper presents the case of a 50-year-old patient with Huntington's disease, repeatedly hospitalized in the Oskar Bielawski Regional Neuropsychiatry Hospital in Koscian. Owing to recurrent aggressive behaviour and to the appearance of positive symptoms, such as persistent persecutory delusions, and also because of lack of cooperation in outpatient care, it was particularly difficult to select appropriate neuroleptic treatment for this patient. The co-occurring symptoms were eventually reduced through the simultaneous use of three antipsychotics in the depot form.