Archive 1995–2023
2012, volume 28, issue 3–4
Case report
Burning mouth syndrome: favourable effect of treatment with olanzapine
Ewa Ferensztajn1,
Dorota Łojko1,
Janusz Rybakowski1
1. Klinika Psychiatrii Dorosłych, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
Farmakoterapia w Psychiatrii i Neurologii, 2012, 3–4, 159–163
Keywords: burning mouth syndrome, treatment, olanzapine, dopamine
Summary
Burning mouth syndrome (BMS) is characterized by chronic burning sensations, pain, paresthesia and dryness within an oral mucosa. BMS can be a variant of neuropathic pain and may be connected with dopaminergic dysfunction of nigrostriatal system. We describe a case of patient with diagnosis of burning mouth syndrome in which a treatment with olanzapine resulted in a rapid, signifi cant improvement of symptoms. The probable mechanism of therapeutic action of olanzapine may be due to the effect of the drug on dopaminergic and histaminergic receptors and, additionally, on noradrenergic and serotonergic receptors.
Correspondence address
Lek. Ewa Ferensztajn
Klinika Psychiatrii Dorosłych
Uniwersytet Medyczny
ul. Szpitalna 27/33, 60-572 Poznań
tel.: +48 61 847 50 87; faks: +48 61 848 03 92
e-mail: [email]ferensztajnewa@gmail.com[/email]
Klinika Psychiatrii Dorosłych
Uniwersytet Medyczny
ul. Szpitalna 27/33, 60-572 Poznań
tel.: +48 61 847 50 87; faks: +48 61 848 03 92
e-mail: [email]ferensztajnewa@gmail.com[/email]