Volume 21, issue 1
Article
Interactions between immune and dopaminergic systems
Ewa Z. Bałkowiec-Iskra1, Iwona Kurkowska-Jastrzębska2
1. Katedra i Zakład Farmakologii Doświadczalnej i Klinicznej Akademii Medycznej w Warszawie
2. II Klinika Neurologiczna Instytutu Psychiatrii i Neurologii w Warszawie
Farmakoterapia w Psychiatrii i Neurologii, 2005, 1, 51-59
Keywords: dopaminergic system, dopamine, immune system, Parkinson's disease, MPTP
Abstract
Studies describing immune system dysfunctions, observed during neurological diseases, let a new branch of science, the neuroimmunology, to be born. In the study, data showing immune system abnormalities accompanied to dopaminergic system changes have been revealed. Influence of dopamine on immune cell functioning as well as decreased concentration of central dopamine on immune system have been described.