Archive 1995–2023
2003, volume 19, issue 4
Article
Influence of dexamethasone on inflammatory reaction and degeneration of dopaminergic neurons in MPTP mice model of Parkinson s disease
Farmakoterapia w Psychiatrii i Neurologii, 2003, 4, 5-20
Keywords: Parkinson’s disease, dexamethasone, neuroprotection
Summary
The authors evaluate the effect of steroids in the mice model of Parkinson’s disease, based on chromatography, Western-blotting and immunohistochemistry. They observed neuroprotective effect of dexamethasone in dose l mg per kilogram body weight. The presume that this effect is associated with anti-inflammatory effect of steroids.