Abstract
Alprazolam as the benzodiazepin preparation, possessing in its chemical structure a triazol ring, by its typical antianxiety (anxiolitic) influences, characterises in antidepressive effect. The purpose of the study led simultaneously in some Polish centers was to estimate clinical efficacy and safety of therapy. Researches in Wrocław were led in 24 patients with a diagnosis of generalized anxiety disorder (GAD), with concomitant depressive symptoms during six weeks lasting treatment with precise range of the dosage. Anxiolitical activity of Xanax significantly manifested after 1 week therapy by a daily dose of about 2 mg and was parallel to an antidepressive effect. Therapeutical effect appeared for a whole period of serving the medicine and wasn't accompanied with serious side symptoms.